Potential Cost-Effectiveness
of Nutrition Interventions to Prevent Adverse Pregnancy Outcomes in the
Developing World
Abstract
The potential cost-effectiveness of
antenatal nutrition interventions to improve pregnancy outcomes in the
developing world has not undergone formal evaluation. Furthermore, the
effectiveness of antenatal care in improving maternal or fetal and neonatal
health has been questioned. However, reasonably compelling evidence from
randomized trials shows that nutrition interventions can prevent both infant
(iodine supplementation) and maternal (vitamin A and β-carotene
supplementation) deaths, and informal analysis suggests that the
cost-effectiveness of nutrition interventions would be comparable and, in some
cases, markedly superior to several standard antenatal interventions. Future
efforts to establish the cost-effectiveness of nutrition interventions in
developing countries will depend on conducting large, pragmatic clinical trials
that use region- and resource-appropriate interventions with mortality or
valid, incontrovertibly severe morbidity endpoints. If such trials establish
effectiveness, credible cost-effectiveness analyses can then be performed.
(Fania Anjela)
(Fania Anjela)
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